能者拿分!谢过了.1.Structure of the Toll-like receptor shown in Figure 33.1 can be described as a __________.a) monomerb) dimerc) trimerd) α2β2 tetramere) α2β2γ2 hexamer2.The leucine-rich repeat domain from human TLR-3 is has a(n) __________ β sheet structure.a) parallelb) antiparallelc) mixedd) cyclice) inverted3.Effector functions of an antibody molecule are carried out by which of its domain(s)?a) one Fab domainb) two Fab domainsc) Fc domaind) Fab and Fc d

能者拿分!谢过了.
1.Structure of the Toll-like receptor shown in Figure 33.1 can be described as a __________.
a) monomer
b) dimer
c) trimer
d) α2β2 tetramer
e) α2β2γ2 hexamer
2.The leucine-rich repeat domain from human TLR-3 is has a(n) __________ β sheet structure.
a) parallel
b) antiparallel
c) mixed
d) cyclic
e) inverted
3.Effector functions of an antibody molecule are carried out by which of its domain(s)?
a) one Fab domain
b) two Fab domains
c) Fc domain
d) Fab and Fc domains together
e) Fab or Fc domain,depending on the particular situation
4.Which of the following incorrectly describes the functionality of the given cell type?
a) B lymphosites:Produce antibodies.
b) cytotoxic T lymphosites:Kill cells that have been invaded by a pathogen.
c) helper T lymphocytes:Stimulate the differentiation and proliferation of B cells and T cells.
d) antigen presenting cells:express class II MHC molecules on the surface.
e) dendritic cells:express CD4 and CD8 molecules on the surface.
2
[For questions 5-7]
5.Which of the above antibody class(es) is generally found in highest concentration in the blood?
a) 1
b) 2
c) 3
d) 1 and 2 both
e) 1 and 3 both
6.Which of the above antibody class(es) constitutes the first line of defense against pathogenic antigens?
a) 1
b) 2
c) 3
d) 1 and 2 both
e) 2 and 3 both
7.Which of the above antibody class(es) appears first in the serum after exposure to an antigen?
a) 1
b) 2
c) 3
d) 1 and 2 both
e) 2 and 3 both
8.Which of the following interactions is usually NOT found at the interface of an antigen and an antibody?
a) hydrogen bond
b) covalent bond
c) electrostatic interaction
d) van der Waals interaction
e) hydrophobic interaction
13.Which selection process(es) suppresses adaptive immune response against self-antigens?
a) positive selection
b) negative selection
c) positive selection followed by negative selection
d) negative selection followed by positive selection
e) positive selection and negative selection simultaneously
4
14.Which of the following diseases is NOT an autoimmune disease?
a) Insulin-dependent diabetes mellitus (also known as type 1 diabetes)
b) multiple sclerosis
c) rheumatoid arthritis
d) AIDS
e) All of the above are autoimmune diseases.
15.Which of the following acronyms are incorrectly described?
a) TLR:Toll-like receptor
b) MHC:Major histocompatibility complex
c) IgG:Immunoglobulin G
d) CDR:cytotoxicity differentiating receptor
e) CD8:cluster of differentiation 8