英语翻译Pretreatment of human monocytes with candesartan significantly decreased Pam3CSK4 or LPSinduced TLR2 and TLR4 expression of both mRNA and protein levels (P and the expression of IL-1\3,IL-6,TNF-\4,and MCP-1专有名字不必翻译出来,monocytes：单核细胞,candesartan：坎地沙坦,其他的不用翻译,直接英文缩写也行,能理解的帮忙下,到底是谁诱导谁的降低和表达.
问题描述：
英语翻译
Pretreatment of human monocytes with candesartan significantly decreased Pam3CSK4 or LPS
induced TLR2 and TLR4 expression of both mRNA and protein levels (P and the expression of IL-1\3,IL-6,TNF-\4,and MCP-1
专有名字不必翻译出来,monocytes：单核细胞,candesartan：坎地沙坦,其他的不用翻译,直接英文缩写也行,能理解的帮忙下,到底是谁诱导谁的降低和表达.
答
使用坎地沙坦（candesartan）对人体单核细胞进行预处理后,单核细胞Toll样受体2（TLR2）和Toll样受体4（TLR4）在Pam3CSK4和脂多糖（LPS）的刺激下所表达的mRNA及蛋白质水平显著下降（P