the patient has tired quite a few kinds of medicine ,but ___had any effect on his disease.

问题描述:

the patient has tired quite a few kinds of medicine ,but ___had any effect on his disease.
A.none
B.nothing
C.neither
D.no one
问其他几个问什么不对?

none是代词,替代前面quite a few kinds of medicine,是否定,没有一个,而nothing指没有东西,neither指对两者的否定,no one一般指人