--______you have done or failed to do, the only approach is to accept it and move forward.为什么答案是regardless of 而不是in spite of 两个不都有不管,不顾的意思吗,什么区别,谢谢

despite意为“不管”“任凭”，相当于in spite of，后接名词、代词或动词，但语气比后者轻，不如后者常用。如: ① He went out despite bad weather. 他不管天气恶劣出发了。② Despite the fogs we went out for a walk. 尽管有雾，我们还是外出散步。
【注】despite后可接what引导的从句如: ① Despite what she says, I'll go.不管她怎么说，我也要去。② I would support him despite what he did. 不管他做什么，我都支持他。
despite = in spite of,故不能再与of连用; in spite of / despite + 名词 = although + 从句
in spite of= despite; regardless of = without considering or taking notice of
regardless of 不管;不顾;不理会.后常接名词或者接从句
in spite of与regardless of区别
前者：一般是主观上故意去忽视，有时往往是好的条件，因素，或他人的建议，很可能导致不好的结果
后者：一般用于客观上无法避免的事实，往往是不利的条件，因素，需要主语去正确面对和处理，并不是避而远之

In spite of all his efforts,his debts continued to mount up .
尽管他做了最大的努力,他的债务还在继续增加.
in spite of尽管的意思
regardless of这里需要用到的是忽略 忽视的意思
明白了吗?