到底神马时候用that 和what (同位语从句中)

问题描述:

到底神马时候用that 和what (同位语从句中)
对比:) I have no idea what has happened to her .
(2) Suddenly the thought came to him that he could go blind.
这两句中what 和that 可以互换吗?

不能替换,(1)句中what在同位语从句中作主语(从句缺了主语)
(2)句中that只起连接作用(因为从句中不缺成分,也没有疑问)