John was _____while the director was out on business

问题描述:

John was _____while the director was out on business
A in the charge
B in charge
C in the charge of
D in charge of

in charge是负责,主管的意思.原句:主任不在时,由John负责
C和D后面有of,都需要跟宾语的,这里没有宾语,所以这两个排除
in the charge被掌管,不符合句意
所以答案B啦